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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XDH
All Species:
37.27
Human Site:
Y744
Identified Species:
82
UniProt:
P47989
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47989
NP_000370.2
1333
146424
Y744
I
G
G
Q
E
H
F
Y
L
E
T
H
C
T
I
Chimpanzee
Pan troglodytes
XP_525729
1333
146376
Y744
I
G
G
Q
E
H
F
Y
L
E
T
H
C
T
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540143
1333
147201
Y745
I
G
G
Q
E
H
F
Y
L
E
T
H
C
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q00519
1335
146500
Y746
I
G
G
Q
E
H
F
Y
L
E
T
H
C
T
I
Rat
Rattus norvegicus
P22985
1331
146224
Y743
I
G
G
Q
E
H
F
Y
L
E
T
N
C
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509432
1297
142673
Q731
K
G
F
A
E
A
D
Q
I
L
E
G
T
G
I
Chicken
Gallus gallus
P47990
1358
149595
Y772
I
G
G
Q
E
H
F
Y
L
E
T
H
C
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688983
1351
148155
Y765
I
G
G
Q
E
Q
F
Y
L
E
T
N
C
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10351
1335
146909
Y749
M
G
G
Q
E
H
F
Y
L
E
T
H
A
A
L
Honey Bee
Apis mellifera
XP_001119950
1356
152206
Y773
T
G
A
Q
E
H
F
Y
L
E
T
N
A
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G192
1321
144562
Y735
L
G
S
Q
Y
V
F
Y
M
E
T
Q
T
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.4
N.A.
89.1
90.3
N.A.
70.4
72.3
N.A.
67.8
N.A.
52.6
52.4
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
95.4
N.A.
95.1
95.8
N.A.
82.3
84
N.A.
81.4
N.A.
69.5
70.5
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
20
93.3
N.A.
80
N.A.
73.3
66.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
26.6
100
N.A.
93.3
N.A.
86.6
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
0
0
0
0
0
0
19
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
91
0
0
0
0
91
10
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
91
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
73
0
0
0
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
73
0
0
0
0
0
55
0
0
0
% H
% Ile:
64
0
0
0
0
0
0
0
10
0
0
0
0
0
55
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
82
10
0
0
0
0
46
% L
% Met:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
91
0
10
0
10
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
91
0
19
73
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _